Anti-HSD11B1 Polyclonal Antibody
产品名称： Anti-HSD11B1 Polyclonal Antibody
英文名称： Anti-HSD11B1 Polyclonal Antibody
产品编号： K002876P
产品价格： null
产品产地： 北京
品牌商标： solarbio
更新时间： 2025-05-30T15:53:18
使用范围： WB
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
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Anti-HSD11B1 Polyclonal Antibody
品牌：solarbio | 货号：K002876P
| 英文名称 | Anti-HSD11B1 Polyclonal Antibody |
|---|---|
| 别名 | 11-DH;11-beta-HSD1;CORTRD2;HDL;HSD11;HSD11B;HSD11L;SDR26C1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 32kDa |
| Gene ID | 3290 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human HSD11B1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human HSD11B1 |
| Subcellular Locations | Endoplasmic reticulum membrane Single-pass type II membrane protein |
| Swiss Prot | P28845 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein. |